Virus hunting

Virus hunting.

Viral diagnosis and discovery are receiving increasing emphasis with the recognition of their importance in addressing the challenges of emerging infectious and chronic diseases, and the advent of antiviral drugs with which to reduce the morbidity and mortality of viral infections. Here we review the status of the field including the use of molecular, proteomic and immunological assays for vira...

"Virus hunting"using radial distance weighted discrimination

Motivated by the challenge of using DNA-seq data to identify viruses in human blood samples, we propose a novel classification algorithm called " Radial Distance Weighted Discrimination " (or Radial DWD). This classifier is designed for binary classification, assuming one class is surrounded by the other class in very diverse radial directions, which is seen to be typical for our virus detectio...

Mutualistic hunting

The cooperative acquisition, defense and distribution of meat are common problems that must be solved by social hunters. These were also problems faced by any of our hominid ancestors that may have hunted large game in our evolutionary past. Much of the last 40 years of research in evolutionary ecology has tried to understand such cooperative behavior. The classic Prisoner's Dilemma game theory...

Hunting dimers

HBCBH and HAlCAlH are related electrondeficient molecules, predicted as local minima on their respective potential energy surfaces. Different views of their electronic structure—as allenes, carbenes, or carbones—prompted two research groups to a friendly competition exploring the predilection of these small molecules to dimerize. Many such dimers emerged from the calculations, some with large e...

Rabbit Hunting